abstract：:Three distinct malathion carboxylesterase (MCE) phenotypes have been identified among strains of Lucilia cuprina. The high-activity phenotype shows 1.6- and 33-fold more MCE specific activity than the intermediate- and low-activity phenotypes, respectively. Flies with high MCE activity are 1000-fold more resistant to ...

journal_title：Biochemical genetics

authors： Smyth KA,Russell RJ,Oakeshott JG

更新日期：1994-12-01 00:00:00

abstract：:To investigate the sex differences of crossing-over in Rana japonica, the recombination frequencies between two linked loci, LDH-B and MPI, were examined in offspring obtained from 29 matings involving either females or males heterozygous at both loci. No recombinants were found among 303 offspring bred from 6 heteroz...

journal_title：Biochemical genetics

authors： Sumida M,Nishioka M

更新日期：1994-10-01 00:00:00

abstract：:A genetic locus controlling the electrophoretic mobility of a methylglyoxal dehydrogenase (EC 1.2.1.23) in the rat is described. The locus, designated Mgd1, is expressed in liver and kidney. Inbred rat strains have fixed either allele Mgd1a or allele Mgd1b. Codominant expression is observed in heterozygotes, providing...

journal_title：Biochemical genetics

authors： Bender K,Seibert RT,Wienker TF,Kren V,Pravenec M,Bissbort S

更新日期：1994-06-01 00:00:00

abstract：:An Italian organophosphate-resistant strain of Culex pipiens (Lucca) was found to be polymorphic for elevated and nonelevated esterases. Selection for high esterase activity produced a strain homozygous for elevated esterases A2 and B2. Selection for low activity produced a strain homozygous for nonelevated esterases,...

journal_title：Biochemical genetics

authors： Callaghan A,Hemingway J,Malcolm CA

更新日期：1993-12-01 00:00:00

abstract：:Genetics and linkage analysis of 6-phosphogluconate dehydrogenase (6-PGD) and malate dehydrogenase (MDH) have been investigated in Anopheles stephensi. Both these markers were found to be autosomal and linked and have been assigned to linkage group III. Two mutant markers, Black larva (Bl) and golden-yellow larva (gy)...

journal_title：Biochemical genetics

authors： Adak T,Subbarao SK,Sharma VP,Rao SR

更新日期：1992-10-01 00:00:00

abstract：:Restriction endonuclease fragment length variations (RFLVs) were detected by using a rat cDNA probe for the bilirubin UDP-glucuronosyltransferase (UDPGT) gene between two mouse strains, 129/Sv and MOL-MIT. RFLVs of the gene were found by EcoRI and PvuII digestions. From linkage analyses of the three-point cross test u...

journal_title：Biochemical genetics

authors： Sato H,Sakai Y,Koiwai O,Watanabe T

更新日期：1992-08-01 00:00:00

abstract：:Male and female wild Norway rats (Rattus norvegicus Erxleben) and male and female albino outbred rats (Ipf:RIZ) were crossbred. These animals were the control, noninbred group (0% inbred). By systematic full-sib mating, two experimental groups (50 and 91% of inbred) were raised. Half of each group (both males and fema...

journal_title：Biochemical genetics

authors： Kosowska B

更新日期：1992-08-01 00:00:00

abstract：:Starch gel electrophoresis and histochemical staining with L-leucylglycyl-glycine revealed genetic polymorphism in peptidase B in cattle erythrocytes. Genetic analysis of 164 full families indicated that the three phenotypes observed are the product of an autosomal locus with two codominant alleles, PepB1 and PepB2. A...

journal_title：Biochemical genetics

authors： Del Lama SN,Del Lama MA,Mestriner MA,Mortari N

更新日期：1992-06-01 00:00:00

abstract：:Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) exhibit genetic polymorphism and tissue specificity. ADH and ALDH isozyme phenotypes from 39 surgical Chinese lung specimens were identified by agarose isoelectric focusing. The identity of the lung beta-ADHs was further demonstrated by their characteristic...

journal_title：Biochemical genetics

authors： Yin SJ,Liao CS,Chen CM,Fan FT,Lee SC

更新日期：1992-04-01 00:00:00

abstract：:Genetic variation of a codominantly inherited pancreas protease, designated CTRA-1, was discovered in the house mouse by isoelectric focusing in polyacrylamide gels. Phenotype CTRA-1A was found in MOLH/Fre and in the majority of common laboratory mouse strains. Phenotype CTRA-1B was found in PWD/Ph. It was characteriz...

journal_title：Biochemical genetics

authors： von Deimling OH,Gröning J,Gaa A

更新日期：1991-12-01 00:00:00

abstract：:Melanoma formation in Xiphophorus hybrids is mediated by a growth factor receptor tyrosine kinase oncogene encoded by the Tu locus. In the wild-type parental fish no tumors occur due to the activity of a locus that regulates the activity of the melanoma oncogene. Molecular identification of this regulatory locus (R) r...

journal_title：Biochemical genetics

authors： Förnzler D,Wittbrodt J,Schartl M

更新日期：1991-12-01 00:00:00

abstract：:In Neurospora crassa, the expression of unlinked structural genes which encode nitrogen catabolic enzymes is subject to genetic and metabolic regulation. The negative-acting nmr regulatory gene appears to play a role in nitrogen catabolite repression. Using the N. crassa nmr gene as a probe, homologous sequences were ...

journal_title：Biochemical genetics

authors： Young JL,Marzluf GA

更新日期：1991-10-01 00:00:00

abstract：:Histone H1 from erythrocytes of Japanese quail was resolved in a sodium dodecyl sulfate (SDS)-polyacrylamide gel into five fractions differing in apparent molecular weights. A polymorphism of histone H1.1, H1.2, and H1.3 bands was detected among quail individuals. While some birds possessed either a high (phenotype .3...

journal_title：Biochemical genetics

authors： Pałyga J

更新日期：1991-10-01 00:00:00

abstract：:Variations at three flight-related enzyme loci, delta-glycerophosphate dehydrogenase (delta-Gpdh), glucose-6-phosphate dehydrogenase (G6pd), and phosphoglucomutase (Pgm), of Epiphyas postvittana (Walker) moths were investigated using starch gel electrophoresis. Among the three enzyme loci, delta-Gpdh and G6pd were fou...

journal_title：Biochemical genetics

authors： Gu HN

更新日期：1991-08-01 00:00:00

abstract：:Gli-D1-encoded omega gliadins of bread wheats show little variation; their electrophoretic patterns can be classified into two main groups which broadly resemble the patterns found in the cultivars Chinese Spring and in Cheyenne. B and D subunits of low molecular weight glutenin encoded by the chromosome 1D loci Glu-D...

journal_title：Biochemical genetics

authors： Masci S,Porceddu E,Lafiandra D

更新日期：1991-08-01 00:00:00

abstract：:DNA polymorphisms in the psi beta 1-beta-globin gene region in nine Asian macaques (Macaca fuscata, M. mulatta, M. nemestrina, M. cyclopis, M. fascicularis, M. arctoides, M. radiata, M. maura, and M. assamensis) were examined using several restriction endonucleasese and the human psi beta 1, delta IVS2, and beta IVS2 ...

journal_title：Biochemical genetics

authors： Shimizu K,Takenaka O

更新日期：1991-04-01 00:00:00

abstract：:Tissue-specific catalase activity in 3-week-old animals from inbred mouse strains 129/ReJ, BALB/c, C3H/HeAnl/Cas-1b, C3H/HeSnJ, C3H/S, C57BL/6J, and Swiss-Webster was found to be highly variable by analysis of variance (P = 0.01). Appropriate crosses were made among strains which were classified as normal (BALB/c, C3H...

journal_title：Biochemical genetics

authors： Schisler NJ,Singh SM

更新日期：1991-02-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) from two breeds of cattle, viz., [Hariana (Bos indicus), Holstein (Bos taurus)] and Indian water buffalo (Bubalis bubalus), was analyzed using 13 restriction endonucleases which recognized an average of about 40 six-base sites. Polymorphism among cattle was detected with six of these enzymes....

journal_title：Biochemical genetics

authors： Bhat PP,Mishra BP,Bhat PN

更新日期：1990-08-01 00:00:00

abstract：:We have isolated the Drosophila melanogaster locus coding for L-glutamate dehydrogenase (EC 1.4.1.3) by virtue of its similarity to the corresponding human gene. There is only one copy of this gene in the fruit fly genome, located on the right arm of chromosome 3 (95D1-4). The transcript includes at least one large in...

journal_title：Biochemical genetics

authors： Papadopoulou D,Louis C

更新日期：1990-08-01 00:00:00

abstract：:Three new linkage groups of enzyme loci are described using Poeciliopsis monacha x P. viriosa-derived interspecific backcross hybrids. Comparison to known linkage groups of the confamilial genus Xiphophorus shows homology between Xiphophorus linkage group I and Poeciliopsis linkage group III, Xiphophorus linkage group...

journal_title：Biochemical genetics

authors： Morizot DC,Schultz RJ,Wells RS

更新日期：1990-02-01 00:00:00

abstract：:Three high-glucose-6-phosphate dehydrogenase (G6PD)-activity mutants (2512H, S44H, and 1FH) are characterized by two insertion sequences associated with the G6PD locus; one (Ins1; 3.5 kb long in 2512H and S44H and 2.9 kb long in 1FH) is present just 5' to exon I and consists of a KP' (the 32nd base of the KP was repla...

journal_title：Biochemical genetics

authors： Itoh M,Iwabuchi M,Yoshida K,Hori SH

更新日期：1989-12-01 00:00:00

abstract：:Stable reciprocal hybrids between Flaveria pringlei (C3) and F. brownii (C4-like) have been produced by standard breeding techniques. There are no differences in the isoelectric focusing patterns of the catalytic subunits of the ribulose-1,5-bisphosphate carboxylase/oxygenase from F. pringlei, F. brownii, or the recip...

journal_title：Biochemical genetics

authors： Johal S,Holaday AS

更新日期：1989-10-01 00:00:00

abstract：:The murine submandibular gland (SMG) produces a novel class of highly acidic salivary proteins encoded by one or more highly abundant mRNA transcripts. In inbred mice, these transcripts are encoded by members of a multigene family comprising approximately 8-12 homologues. Most, and probably all, of these homologues ar...

journal_title：Biochemical genetics

authors： Dickinson DP,Abel K,Near J,Taylor BA,Gross KW

更新日期：1989-10-01 00:00:00

abstract：:Techniques for performing numerous enzyme kinetic assays with minimum time and effort would be valuable to studies of the evolutionary genetics of metabolic control and the quantitative genetics of determinants of kinetic parameters. Microtiter plate readers have been used for a variety of repetitious analytical techn...

journal_title：Biochemical genetics

authors： Clark AG,Keith LE

更新日期：1989-06-01 00:00:00

abstract：:High levels of nuclease activities were identified in filtrates of Aspergillus cultures after growth in low-but not in high-phosphate media. Deoxyribonuclease activities, characterized extensively by column chromatography, showed a coincident single peak for ss- and ds-DNase which was distinct from the peak for RNase....

journal_title：Biochemical genetics

authors： Käfer E,Tittler A,Fraser MJ

更新日期：1989-04-01 00:00:00

abstract：:Differences in Zn-induced levels of hepatic metallothionein (MT) in inbred strains of the mouse are described. Three low-producing strains, C57 BL/6, C57BL/10, and NIH, are identified, while C3H and CBA display the highest levels of hepatic MT following Zn treatment. These interstrain differences affect not only the l...

journal_title：Biochemical genetics

authors： Farr C,Hunt DM

更新日期：1989-04-01 00:00:00

abstract：:The gliadin composition of 78 spring durum wheat varieties has been studied by one-dimensional (Al-lactate, pH 3.1) and two-dimensional (first dimension, Al-lactate, pH 3.1; second dimension, sodium dodecyl sulfate-polyacrylamide gel) electrophoresis. Analysis of hybrids has shown that all components of the alpha zone...

journal_title：Biochemical genetics

authors： Kudryavtsev AM,Metakovsky EV,Sozinov AA

更新日期：1988-12-01 00:00:00

abstract：:Two types of alleles exist in the human alcohol dehydrogenase-2 (ADH2) locus. The usual ADH12 allele is common in Caucasians, while the atypical ADH22 allele is predominant in Orientals. The ADH22 produces the beta 2 subunit, which is catalytically far more active than the beta 1 subunit produced by the ADH12 gene. Th...

journal_title：Biochemical genetics

authors： Ikuta T,Shibuya A,Yoshida A

更新日期：1988-08-01 00:00:00

abstract：:Chromosomal locations of 10 isozyme loci in rice (Oryza sativa L.) were determined through trisomic analysis. All 10 genes produced altered allozyme banding patterns in specific F1 trisomics. This served as the primary source of evidence for chromosome locations of Est-5, Icd-1, Acp-1, and Pgd-1. The locations of Amp-...

journal_title：Biochemical genetics

authors： Wu KS,Glaszmann JC,Khush GS

更新日期：1988-04-01 00:00:00

abstract：:The soluble proteins of the normal and male-sterile stamenless-2 (sl-2/sl-2) mutant of tomato (Lycopersicon esculentum) grown in different temperatures were analyzed by one- and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The normal and mutant stamens had some common proteins, but certai...

journal_title：Biochemical genetics

authors： Sawhney VK,Bhadula SK

更新日期：1987-10-01 00:00:00

abstract：:UMP synthase was characterized biochemically in dairy cattle heterozygous for a deficiency of this enzyme. Both activities comprising this bifunctional enzyme are decreased, with OMP decarboxylase more affected than orotate phosphoribosyltransferase. Immunotitration of UMP synthase activity revealed the presence of th...

journal_title：Biochemical genetics

authors： Harden KK,Robinson JL

更新日期：1987-08-01 00:00:00

abstract：:Two electrophoretic variants of adenine phosphoribosyltransferase (APRT) were identified in a population of wild mice (Mus musculus bactrianus). Breeding tests demonstrated that the APRT variants are under the control of two alleles at an autosomal locus designated Aprt. We have examined the linkage relationships betw...

journal_title：Biochemical genetics

authors： Nesterova TB,Borodin PM,Zakian SM,Serov OL

更新日期：1987-08-01 00:00:00

abstract：:The aryl hydrocarbon hydroxylase (Ah) locus that controls the induction of chemical carcinogen-metabolizing enzymes in mice has been found to be linked to a new restriction-fragment length polymorphism (RFLP). Only C57BL/6 and closely related inbred strains displayed a 7.6-kb HindIII restriction fragment, while all ot...

journal_title：Biochemical genetics

authors： Cobb RR,Stoming TA,Whitney JB 3rd

更新日期：1987-06-01 00:00:00

abstract：:Genetic analysis of a polymorphic tissue esterase revealed a new locus (Est-6) with two alleles (Est-6a and Est-6b) on linkage group VI of the rabbit. Est-6 is closely linked to the Est-1,2,4 cluster. Esterase of Est-6 is found in many organs, particularly in liver and small intestine, but not in erythrocytes and seru...

journal_title：Biochemical genetics

authors： van Zutphen LF,den Bieman MG,von Deimling O,Fox RR

更新日期：1987-06-01 00:00:00

abstract：:Glucose-6-phosphate dehydrogenase (G6PD) deficiency was identified in two children who were studied because of hemolytic episodes. The electrophoretic and kinetic properties of the mutant enzymes allowed us to conclude that both of them were new variants. They were named G6PD Guantánamo and G6PD Caujerí. ...

journal_title：Biochemical genetics

authors： Gutiérrez A,García M,Estrada M,Quintero I,González R

更新日期：1987-04-01 00:00:00

abstract：:The solubilized proteins of liver and brain from mice of two inbred strains (C57BL/6J and DBA/2J) and their hybrids were subfractionated by heparin Sepharose (H-S) CL-6B affinity chromatography. The H-S binding and nonbinding proteins were separated by two-dimensional electrophoresis. The protein patterns obtained wer...

journal_title：Biochemical genetics

authors： Jungblut P,Klose J

更新日期：1986-12-01 00:00:00

abstract：:The aldox-2 locus in Drosophila melanogaster has been shown to affect differentially three molybdoenzymes, aldehyde oxidase, pyridoxal oxidase, and xanthine dehydrogenase. These effects are most obvious at times surrounding the pupal-adult boundary, when the normal organism accumulates large amounts of these enzymes i...

journal_title：Biochemical genetics

authors： Meidinger RG,Bentley MM

更新日期：1986-10-01 00:00:00

abstract：:Fourteen myoglobins of known sequence were examined by isoelectric focusing with and without urea. The 14 sequences formed six distinct mobility classes on gels without urea and three classes on those with urea. For these proteins, isoelectric focusing provides no advantage over single, nonequilibrium, nondenaturing g...

journal_title：Biochemical genetics

authors： McLellan T,Inouye LS

更新日期：1986-08-01 00:00:00

abstract：:Examination of eight Atlantic species of the genus Littorina by starch gel electrophoresis of purine nucleoside phosphorylase revealed extensive polymorphism within the L. saxatilis complex. In this group, four alleles have been identified. Heterozygotes are four banded, and thus, as in vertebrates, the enzyme is like...

journal_title：Biochemical genetics

authors： Knight AJ,Ward RD

更新日期：1986-06-01 00:00:00

abstract：:Active-site tryptic peptides were isolated from three genetic types of human serum cholinesterase. The active-site peptide was identified by labeling the active-site serine with [3H]diisopropylfluorophosphate. Peptides were purified by high-performance liquid chromatography. Amino acid composition and sequence analysi...

journal_title：Biochemical genetics

authors： Lockridge O,La Du BN

更新日期：1986-06-01 00:00:00